Vascular smooth muscle cell atherosclerosis trajectories characterized at single cell resolution identify causal transcriptomic and epigenomic mechanisms of disease risk
Daniel Yuhang Li, Soumya Kundu, Paul P. Cheng, Wenduo Gu, Matthew D. Worssam, William Jackson, Quanyi Zhao, Trieu Nguyen, A. Y-C. Yu, João P Monteiro, Roxanne Diaz Caceres, Stanley Dale, Brian T. Palmisano, Chad S. Weldy, Markus O Ramste, , Thomas Quertermous
The paper characterizes atherosclerosis trajectories in vascular smooth muscle cells using single-cell data and identifies causal transcriptomic and epigenomic mechanisms of CAD risk.
Nature Communications · Mar 17, 2026Peer-reviewedGenomics