Author

Xiaolin Zhou

Centre for Addiction and Mental Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Bowen HuiD· 1 shared Etienne L. SibilleiD· 1 shared Guillermo González‐BurgosiD· 1 shared Jian Rao· 1 shared Jianwei Wang· 1 shared Keon ArbabiiD· 1 shared Kui Xu· 1 shared Laramie E. DuncaniD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Bowen HuORCID

Author profile →

3 papers

Recent·Most cited

Functional reorganization of large-scale brain systems underlies emotion regulation maturation

Rui Ding, Zhi Zhang, Ze Zhang, Ruoting Qing, Bowen Hu, Qi Huang, Yi Luo, Yi Hu, Xiaolin Zhou, Shaozheng Qin

This study shows that emotion regulation maturation involves reorganization of distributed brain systems rather than just strengthening prefrontal control, with key developmental changes in specific brain regions and networks.

bioRxiv · Sep 22, 2026 · PreprintNeuroscience

Selective depletion of upper-layer somatostatin interneuron subtypes in schizophrenia

Nicole Endresz, Maria Eleni Fafouti, Keon Arbabi, Xiaolin Zhou, Thomas DeLong, Guillermo González‐Burgos, Laramie E. Duncan, Etienne L. Sibille, Shreejoy J. Tripathy

The paper identifies reduced SST mRNA and depletion of specific upper-layer Sst interneurons in schizophrenia using single-nucleus RNA-seq and spatial transcriptomics.

bioRxiv · Sep 22, 2026 · PreprintBioinformatics

In vivo structural characterization of the whole SARS-CoV-2 RNA genome identifies host cell target proteins vulnerable to re-purposed drugs

Lei Sun, Pan Li, Xiaohui Ju, Jian Rao, Wenze Huang, Shaojun Zhang, Tuanlin Xiong, Kui Xu, Xiaolin Zhou, Lili Ren, Qiang Ding, Jianwei Wang, Qiangfeng Cliff Zhang

The paper maps the in vivo structure of SARS-CoV-2 RNA, identifies novel structural features, and predicts host proteins interacting with the RNA using deep learning.

Cell · Apr 1, 2021Peer-reviewedMicrobiology