Author

Xu-Dong Wang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Yonghao YuiD· 2 shared An-Dao Yang· 1 shared Andrea J. BermaniD· 1 shared Anne K. Hollensen· 1 shared Bruno D. FonsecaiD· 1 shared Chiho KimiD· 1 shared Christian K. Damgaard· 1 shared Christopher Dajadian· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Yonghao YuORCID

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2 papers

Recent·Most cited

PARP1 inhibitors trigger innate immunity via PARP1 trapping-induced DNA damage response

Chiho Kim, Xu-Dong Wang, Yonghao Yu

This study identifies PARP1 trapping as the key mechanism by which PARP inhibitors trigger innate immunity, while PARP1 degraders avoid this response.

bioRxiv · Jul 12, 2020Cancer Biology

LARP1 is a major phosphorylation substrate of mTORC1

Bruno D. Fonseca, Jian-Jun Jia, Anne K. Hollensen, Roberta Pointet, Huy-Dung Hoang, Marius R. Niklaus, Izabella A. Pena, Roni M. Lahr, Ewan M. Smith, Jaclyn Hearnden, Xu-Dong Wang, An-Dao Yang, Giovanna Celucci, Tyson E. Graber, Christopher Dajadian, , Tommy Alain

This study identifies LARP1 as a major phosphorylation substrate of mTORC1 and elucidates its role in regulating TOP mRNA translation.

bioRxiv · Dec 8, 2018 · PreprintBiochemistry