Neofunctionalized carbonic anhydrases in the biosynthesis of neuroactive plant alkaloids
R. S. Nett, Y. Dho, C. Tsai, D. Wonderlick, Y.-Y. Low, E. S. Sattely
The paper identifies neofunctionalized carbonic anhydrases involved in the biosynthesis of neuroactive Lycopodium alkaloids and describes their role in scaffold tailoring for acetylcholinesterase inhibition.
bioRxiv · Nov 1, 2022 · PreprintBiochemistry