Synthetase and Hydrolase Specificity Collectively Excludes Deoxyguanosine from Bacterial Alarmone
R. W. Zhou, I. J. Gordon, Y. Hei, B. Wang
The paper shows that bacterial alarmone synthetases and hydrolases exclude 2-deoxyguanosine due to its inability to be degraded, preventing deleterious 2dG alarmone production.
bioRxiv · Jan 6, 2024 · PreprintMicrobiology