The evolutionary history of class I aminoacyl-tRNA synthetases indicates early statistical translation
Jagoda Jabłońska, Yao Chun-Chen, Liam M. Longo, Dan S. Tawfik, Ita Gruic‐Sovulj
This study reconstructs the evolutionary history of Class I aminoacyl-tRNA synthetases, finding that early AARSs were generalists capable of charging a wide range of amino acids, suggesting statistical translation evolved before specialized, accurate translation.
bioRxiv · Jun 9, 2022 · PreprintBioinformatics