Remote immune processes revealed by immune-derived circulating cell-free DNA
Ilana Fox-Fisher, Sheina Piyanzin, Bracha-Lea Ochana, Agnes Klochendler, Judith Magenheim, Ayelet Peretz, Netanel Loyfer, Joshua Moss, Daniel Cohen, Yaron Drori, Nehemya Friedman, Michal Mandelboim, Marc E. Rothenberg, Julie M. Caldwell, Mark Rochman, , Yuval Dor
The paper uses immune cell type-specific methylation patterns in circulating cell-free DNA to monitor immune dynamics and find that immune-derived cfDNA levels reflect immune homeostasis and predict immune responses to perturbations.
eLife · Nov 26, 2021Peer-reviewedGenomics