ImmunologybioRxivPreprint
CXCL13/CXCR5 Chemokine Axis Promotes CXCR5+CD19+ B-Cell and Follicular/Effector CXCR5+CD4+ T-Cell Responses in the Lungs Associated with Protection from Severe and Fatal COVID-19 Following Infection with Pathogenic SARS-CoV-2 Delta Variant
Hawa Vahed, Aziz Alami Chentoufi, Swayam Prakash…·Lbachir BenMohamed
This study shows that CXCL13 deficiency in mice worsens SARS-CoV-2 infection, with higher viral load, lung damage, and reduced B and T cell responses.
DOI 10.1101/2025.04.18.649623