BC-Design: A Biochemistry-Aware Framework for Inverse Protein Design
Xiangru Tang, Xinwu Ye, Fang Wu, Yimeng Liu, Anna Su, Antonia Panescu, Guanlue Li, Daniel Shao, Dong Xu, Mark Gerstein
BC-DO_SCPLOWESIGNC_SCPLOW improves inverse protein design by integrating continuous physicochemical properties with structural geometry, achieving high sequence recovery and functional design accuracy.
bioRxiv · Oct 28, 2024 · PreprintBioinformatics