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2 papers
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Silk J. Shi, Yingjun Lin, Epic Z. Fu, Hermia M. Xu, Robert J. Yang, Yaphia Y. Zhao, Jason Z. Ye, Jack F. Hong, Amy Y. Chen, Xingjian Bai, Bruce T. Lahn
MuteFree eliminates ITR mutations in AAV transfer plasmids, achieving 0% mutation rates and resolving production issues in GMP manufacturing.
bioRxiv · Apr 9, 2026 · PreprintMolecular Biology
Silk J. Shi, Yingjun Lin, Jason Z. Ye, A Kwok, Kyrie Z. Want, Jesse Z. Cai, Mina M. Hu, Arianna Y. Liu, Kyler J. Li, Bernice Y. Guo, Herman H. Xia, Evian P. Huang, Julia X. Chen, Jack F. Hong, Cole K. Zheng, Bruce T. Lahn
miniVec is a new plasmid backbone that eliminates antibiotic resistance genes and improves plasmid yield and functionality for clinical applications.
bioRxiv · Oct 2, 2025 · PreprintBioengineering