Author

Yuan Lin

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:benchmarking· 2 Approach:machine learning (classical)· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:plant (other)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Baosheng N/A FengiD· 1 shared Bing HaoiD· 1 shared Chang Chen· 1 shared Chaoyu Lei· 1 shared Geng CheniD· 1 shared Guanghui ZhangiD· 1 shared Guisheng XiangiD· 1 shared Houston Culpepper· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Baosheng N/A FengORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Assessing and Optimizing Low-Frequency Somatic Mutation Detection: A Multi-Platform High-Throughput Sequencing Perspective

Baosheng N/A Feng, Yixin Lin, Lei Liu, Qunting Lin, Yuan Lin, Yongfang Liu, Jiatao Li, Chaoyu Lei, Chang Chen, Manman Yang, Xuejie Peng, Zhiliang Zhou, Qin Yan, Lei Sun, Qigang Li

This study evaluates and improves low-frequency somatic mutation detection across multiple sequencing platforms using a simulated benchmark and a machine learning-based caller.

bioRxiv · Jun 3, 2026 · PreprintBioinformatics

Pathway elucidation of pharmaceutical cucurbitacin IIa in Hemsleya chinensis and high-level production of precursor cucurbitadienol in engineered Saccharomyces cerevisiae and Nicotiana benthamiana

Geng Chen, Zhaokuan Guo, Yan Zhao, Yanyu Shu, Lei Qiu, Shao-feng Duan, Yuan Lin, Simei He, Xiaobo Li, Xiao‐Lin Feng, Guisheng Xiang, Yang Shi, Sheng-Chao Yang, Guanghui Zhang, Bing Hao

This study elucidates the biosynthetic pathway of cucurbitacin IIa in Hemsleya chinensis and demonstrates high-level production of its precursor in yeast and tobacco.

bioRxiv · Sep 28, 2022 · PreprintSynthetic Biology

SAFE-clustering: Single-cell Aggregated (From Ensemble) Clustering for Single-cell RNA-seq Data

Yuchen Yang, Ruth Huh, Houston Culpepper, Yuan Lin, Michael I. Love, Yun Li

SAFE-clustering integrates multiple clustering methods to improve accuracy and robustness in scRNA-seq data analysis, reducing cluster deviation and improving assignment compared to individual methods.

Bioinformatics · Sep 6, 2018Peer-reviewedBioinformatics