Characterization of the somatic landscape and transcriptional profile of breast tumors from 748 Hispanic/Latina women in California
Yuanchun Ding, Rosalyn W. Sayaman, Denise M. Wolf, Joanne E. Mortimer, Allen Mao, Laura Fejerman, Stephen B. Gruber, Stephen Starko Francis, Susan L. Neuhausen, Elad Ziv
The paper analyzes somatic mutations and transcriptional profiles in breast tumors from 748 Hispanic/Latina women, finding differences in tumor immune microenvironment ecotypes linked to ancestry and APOBEC3A/B copy-number deletions.
medRxiv · May 27, 2026 · PreprintGenetic & Genomic Medicine