Kingdom-wide Discovery of Type VI Secretion Effectors via AI Uncovers Three New Bacterial Toxins
Avital Akerman-Arad, Aleks Danov, Yuval Chausho, Aya Friedman, Shai Benedict, Maor Shalom, Tal Fisher, Rina Fraenkel, Gideon Mamou, Yaara Oppenheimer-Shaanan, Netanel Tzarum, Asaf Levy
The paper uses an XGBoost classifier to identify novel T6SS effectors in bacterial genomes, validating three new toxins with cytotoxic effects and structural features.
bioRxiv · Sep 28, 2026 · PreprintMicrobiology