Machine Learning Investigation Of Gene Expression Datasets Reveals TP53 Mutant-like AML With Wild Type TP53 And Poor Prognosis
Y. Lee, L. B. Baughn, Z. Sachs, C. L. Myers
This study uses machine learning to identify a TP53 mutant-like AML subtype with poor prognosis in TP53 wild-type cases, characterized by distinct gene expression and drug sensitivity profiles.
bioRxiv · Feb 22, 2023 · PreprintCancer Biology