Oncostatin M-driven leak in human endothelial cells with preserved tight junctions
Giulio Fulgoni, Francesc López‐Giráldez, Zenaat Malik, Guilin Wang, Elena Wilson, Clancy W. Mullan, Weiming Ni, Xinran Nick Liu, Feng‐Xia Liang, C. Shan Xu, Song Pang, Edward Vincent S. Faustino, Jordan S. Pober, Richard W. Pierce
This study identifies oncostatin M-driven vascular leak in human endothelial cells through nanoscale channel formation, distinct from junction disassembly, and highlights potential therapeutic targets.
bioRxiv · Oct 29, 2026 · PreprintCell Biology