Follistatin-like protein 1 interacts with programmed cell death 4 to promote vascular mimicry in hepatocellular carcinoma by activating the PI3K/AKT/mTOR signaling pathway
Zhaowei Yang, Jiajing Zhu, Huan Chen, Jin Liu, Wenjia Tan, Hang Li
This study identifies FSTL1's role in promoting vascular mimicry in HCC via interaction with PDCD4 and activation of the PI3K/AKT/mTOR pathway, suggesting it as a potential therapeutic target.
bioRxiv · Apr 30, 2025 · PreprintCancer Biology