Dopamine and serotonin transients predict depressive symptom relief following deep brain stimulation of human subcallosal cingulate cortex
Blair R. K. Shevlin, Qi Xiu Fu, Seth R. Batten, Brian Harris Kopell, Arianna Neal Davis, Matthew Heflin, Stephen Heisig, Christopher J. Rozell, Ayaka Kato, Kaustubh R. Kulkarni, Ki Sueng Choi, Ha Neul Song, Shannon K. O’Neill, Tanya Nauvel, Isha Trivedi, , Xiaosi Gu
This paper shows that dopamine and serotonin changes during deep brain stimulation predict symptom relief in treatment-resistant depression.
Biological Psychiatry · Apr 25, 2026Peer-reviewedNeuroscience