Author
University of HelsinkiORCID 0000-0001-9928-1663Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Anil Kumar Giri, Jake Lin, Konstantinos Kyriakidis, Garima Tripathi, Henrikki Almusa
BMC Medical Genomics · Apr 4, 2025Peer-reviewedGenetic & Genomic Medicine
Karoliina Salenius, Niina Väljä, Sini Thusberg, François Iris, Christine Ladd‐Acosta, Christophe Roos, Matti Nykter, Alessio Fasano, Reija Autio, Jake Lin
The paper performs a multivariate GWAS on autism and 8 co-occurring conditions, identifying 637 significant genetic associations and novel genes linked to autism and related traits.
medRxiv · Jan 7, 2024 · PreprintGenetic & Genomic Medicine
Sanni Ruotsalainen, Juulia Partanen, Anna Cichońska, Jake Lin, Christian Benner, Ida L. Surakka, FinnGen, Aarno Palotie, Mark J. Daly, Pharmaceutical companies, Howard J. Jacob, Athena Matakidou, Heiko Runz, Sally John, Robert M. Plenge, , Kari Linden
The paper introduces a multivariate GWAS framework that identifies functional variants and disease associations by transforming multivariate results into univariate phenotypes for follow-up analysis.
European Journal of Human Genetics · Oct 27, 2020Peer-reviewedGenetics
Jake Lin, Rubina Tabassum, Samuli Ripatti, Matti Pirinen
MetaPhat decomposes multivariate GWAS associations into central traits using BIC and P-value statistics, improving interpretation of genotype-phenotype links.
Frontiers in Genetics · May 15, 2020Peer-reviewedGenetics
Juha Mehtonen, Petri Pölönen, Sergei Häyrynen, Jake Lin, Thomas Liuksiala, K Granberg, Olli Lohi, Ville Hautamäki, Matti Nykter, M. Heinäniemi
The paper develops a method for stratifying molecular profiles across datasets and applies it to hematological malignancies, revealing differential DNA methylation in a leukemia cluster.
bioRxiv · Jan 15, 2018 · PreprintBioinformatics