A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits
Zhu Meng, Shiwen Zhang, Ziyang Zhuang, Jiayi He, Fei Liu, Lingyun Wu, Xiangrong Sun, Jingsheng Lu, Xinyi Li, Hao Yang, Mian Gong, Xiaolong Du, Qiao Mei, Hao Li, Guoqing Zhang, , Zhangyuan Pan
SheepEpimap combines 516 histone CUT&Tag, ATAC-seq and RNA-seq datasets from 43 sheep tissues to annotate 2.93 million cis-regulatory elements and 145,407 allele-specific variants for trait interpretation.
bioRxiv · Aug 26, 2026 · PreprintGenetics✦ In-depth digest