Author

H Kobayashi

Fujifilm (Japan)ORCID 0009-0000-5646-059XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hiroshi KatoiD· 2 shared Setsu Endoh‐YamagamiiD· 2 shared Akira Nabetani· 1 shared Euikyung Shin· 1 shared Kenichi Kazetani· 1 shared Kiyohiro MaedaiD· 1 shared Mitsuho Taniguchi· 1 shared Takashi Wakui· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 23 mutual co-author links

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2 shared papersNeuroscience

Hiroshi KatoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The tri-culture system reveals an activation cascade from microglia through astrocytes to neurons during neuroinflammation

H Kobayashi, Hiroshi Kato, Mitsuho Taniguchi, Setsu Endoh‐Yamagami

The paper develops a tri-culture system of human neurons, astrocytes, and microglia to study neuroinflammation and reveals a cascade of activation from microglia to astrocytes to neurons.

Journal of Neurochemistry · Mar 1, 2026Peer-reviewedNeuroscience

Human aged astrocytes induce neurotoxicity in response to inflammatory stimuli

H Kobayashi, Kiyohiro Maeda, Takashi Wakui, Kenichi Kazetani, Akira Nabetani, Euikyung Shin, Hiroshi Kato, Setsu Endoh‐Yamagami

This study shows that aged human astrocytes are more neurotoxic than young ones when exposed to inflammatory stimuli, suggesting a link between aging and neurodegenerative diseases.

bioRxiv · Aug 17, 2025 · PreprintNeuroscience