Head and Neck Cancer Studies

Predicting Pathway Dependency in Head and Neck Squamous Cell Carcinoma from Hallmark Transcriptomic Features

The paper develops a transcriptome-based framework to predict pathway dependency in HNSCC using Hallmark features, finding HPV+ tumors show higher dependency in seven pathways.

HPV-Associated Tonsillar Intraepithelial Neoplasia and Oral High-Risk HPV mRNA as a Candidate Biomarker

The paper identifies HPV-associated premalignant lesions in tonsils and suggests oral HR-HPV mRNA as a potential biomarker for early detection.

Spatiotemporal Heterogeneity of HPV Integration Architectures Drive Oncogenic Features of Oropharyngeal Cancer

The paper characterizes HPV integration structures in oropharyngeal cancer and links Type2 integration to oncogenic features and aggressive tumor behavior.