Ferroptosis and cancer prognosis

Establishment of a prognosis prediction model based on pyroptosis-related signatures associated with the immune microenvironment and molecular heterogeneity in clear cell renal carcinoma

The paper identifies two pyroptosis subtypes in ccRCC and constructs a prognosis prediction model based on pyroptosis-related risk scores.

Microglia ferroptosis is prevalent in neurodegenerative disease and regulated by SEC24B

The paper shows microglia are susceptible to ferroptosis in neurodegenerative diseases and identifies SEC24B and small molecules that regulate this process.

Pyroptosis-related gene signatures can robustly diagnose skin cutaneous melanoma and predict the prognosis

The paper identifies 20 pyroptosis-related genes that can diagnose skin cutaneous melanoma and predict prognosis using machine learning and survival analysis.

Identification of the Novel Pyroptosis-Related Gene Signature in Patients with Esophageal Adenocarcinoma

The paper identifies a five-gene pyroptosis-related signature associated with survival in esophageal adenocarcinoma patients using TCGA data.

Identification and verification of the potential effect of therapeutic miRNA-mRNA pairs on ferroptosis in small cell lung cancer by bioinformatics analysis

The paper identifies and verifies potential therapeutic miRNA-mRNA pairs affecting ferroptosis in SCLC using bioinformatics analysis and validation with additional data.

A Compendium of Kinetic Cell Death Modulatory Profiles Identifies Ferroptosis Regulators

The paper identifies ferroptosis regulators using a compendium of kinetic cell death modulatory profiles from 1,833 small molecules.

Systematic identification of a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis

The paper identifies a nuclear receptor-enriched predictive signature for erastin-induced ferroptosis using gene expression analysis and pharmacogenomics datasets.