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The paper compares RNA sequencing protocols using long-read sequencing, finding significant changes in isoform structure and abundance due to RNA processing steps.

This paper investigates the structural feasibility of squalene interacting with the KEAP1 Kelch domain using molecular docking and provides a hypothesis for its role in NRF2 regulation under stress.

This study shows antibiotic-induced envelope stress in Salmonella disrupts compartmentalization, enabling PBP5 and ACP interaction that drives hypervesiculation.

This study introduces QUEST, a model that uses H&E histology to predict spatial protein expression, enabling virtual staining and analysis across biological scales.

ALIGN provides a modular framework for analyzing longitudinal development in C. elegans, enabling accurate segmentation, quality control, and motion correction across imaging conditions.

The paper shows that environmental-induced phenotypic plasticity can promote coexistence in antagonistic bacterial species by spatial segregation, but removing this segregation leads to higher coexistence through adaptive plasticity.

This study shows that rats integrate taste and smell signals differently depending on the valence of flavor components, challenging the MLE framework for multisensory integration.

This study shows that PXR expression in melanoma cells increases sensitivity to BRAFi/MEKi treatment and is linked to a melanocytic phenotype.

HiFiTaxa is a Nextflow pipeline for analyzing PacBio HiFi reads of 16S rRNA and ITS amplicons, offering multiple classifiers and benchmarking their performance on mock communities and holdouts.

This study introduces RECON, a technique that dynamically controls DNA conformations in nanowells, enabling access to non-equilibrium states through periodic and stochastic signals.

This paper shows that artificial diving reflex via trigeminal nerve stimulation activates NRF2 through p62 phosphorylation, offering neuroprotection in traumatic brain injury without depleting antioxidant reserves.

This study disentangles visual and motor contributions to tracking performance in continuous psychophysics by analyzing cross-correlogram metrics under visual impairment and hand dominance conditions.

This study investigates the effects of natural daylight and physical activity on circadian phase using a Bayesian crossover experiment, finding inconclusive results.

This study uses TMS-EEG and a new toolbox to analyze cortical recovery dynamics after perturbation, finding that extended post-stimulation analysis reveals LICI-related differences in resilience and temporal memory.

Astex-Faro improves cryo-EM hit identification by detecting structural deviations and enhancing weak features across diverse datasets.

This study identifies a rare pancreatic tissue-resident regulatory T cell population that exhibits both anti-tumour and pro-repair functions in the exocrine pancreas.

This study identifies genetic regulators of sugar-dependent food consumption in Drosophila using GWAS and RNAi knockdown.

This study shows how antibody structure affects FcRn recycling and pharmacokinetics, finding that invertbody design reduces clearance by threefold.

This study shows that PTEN inhibition improves forelimb motor recovery and circuit remodeling in chronic cervical SCI by enhancing spinal interneuron network recruitment and synaptic input.

This study identifies anti-phage defense systems in VREfm genomes and finds limited associations between specific systems and phage resistance, with one candidate gene reducing susceptibility.