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This study investigates how a genetic polymorphism in ADRA2B affects responses to vagus nerve stimulation, finding it influences pupillary responses and cortical activity alignment with noradrenergic projections.

This study shows that standard touchscreen testing in mice shifts circadian rhythms and proposes a modified protocol to reduce these effects without affecting cognitive performance.

This study shows imipramine binds to amyloid-β, reduces Aβ accumulation, and improves survival in Alzheimer's patients.

The paper uses a 3D CLL spheroid model to study how lymph node microenvironmental signals influence CLL cell phenotypes and drug responses to ibrutinib.

The paper analyzes brain-wide neural activity in C. elegans during olfactory navigation and identifies functional circuits linking sensory input to motor behavior across different environments and behavioral states.

This study tests using concrete waste to supply calcium and alkalinity for coccolithophore cultivation, showing increased calcite production and CO2 removal potential.

This study shows that CTLA-4 signaling impairs antibody quality during Borrelia infection by affecting germinal center dynamics and T cell responses in mice.

FedEpitope uses federated learning with LoRA to predict linear B-cell epitopes without centralizing data, achieving good performance across multiple clients.

This study examines how elevated temperature and CO2 affect Wolbachia abundance and host fitness in a stored-product pest, finding stable cytoplasmic incompatibility despite changes in Wolbachia dynamics.

This paper develops a mouse model of metastasis-induced breast cancer cachexia and identifies that anorexia drives tissue wasting while muscle weakness is independent of food intake.

This study shows chronic hypertension increases BBB permeability and anxiety-like behaviors in female rats but not males in a vascular cognitive impairment model.

The paper analyzes the dynamics of a whole-mouse-brain neural mass model coupled via an empirical connectome, finding chaotic oscillations and suppression of chaos with network modifications.

This study reconstitutes lipid nanoparticle-mediated siRNA transfer across endosomal membranes using GUVs, showing siRNA can translocate without membrane rupture or pH gradient loss.

This study compares hydroponic and substrate-based methods for evaluating pea genotype resistance to Fusarium oxysporum, finding hydroponics more sensitive in distinguishing susceptible genotypes.

This paper introduces a phase decoder that reconstructs missing muscle activity from sparse EMG signals, achieving accurate phase estimation and muscle activation reconstruction in real-time.

This study shows that mitovesicles from Alzheimer's disease mouse models undergo stage-specific proteomic changes that reflect mitochondrial dysfunction and provide a conserved disease signature in humans.

The paper uses enzyme-constrained metabolic modeling to show that Picochlorum celeri's rapid growth at elevated CO2 is due to protein budget allocation, not enzyme abundance.

This study shows that oscillatory phase coding emerges in adaptive RNNs during sequence working memory tasks, with phase encoding serial order and amplitude encoding item identity.

This study shows UCS in zebrafish alters exploratory behavior patterns, with method-dependent identification of resilient-like archetypes.