Mechanisms of impaired cerebral hemodynamics and memory resilience differ by sex: A role for mineralocorticoid receptors in VCID
Gianna M DeMarco, Gabrielle A Bernstein, Dinlin Chen, James Bloete, Emily D Schellinger, Maya E Westbrook, Emily J Baumoel, Jared Luchetta, Abbie C Chapman
This study investigates sex-specific effects of hypertension on cerebral hemodynamics and memory, finding that MR antagonism improves perfusion and memory in female rats but not males.
bioRxiv · Nov 4, 2026 · PreprintNeuroscience