A CRISPRi Library Screen in Group B Streptococcus Identifies Surface Immunogenic Protein (Sip) as a Mediator of Multiple Host Interactions
Kyle Firestone, Kathyayini P. Gopalakrishna, Lisa M. Rogers, A Peters, Jennifer Angeline Gaddy, C Nichols, MH Hall, HN Varela, Sophia M. Carlin, Gideon H. Hillebrand, Elizabeth J. Giacobe, David Michael Aronoff, Thomas Alexander Hooven
This study uses CRISPRi to identify Sip as a key surface protein in GBS that modulates host interactions and pathogenesis.
Infection and Immunity · Mar 21, 2025Peer-reviewedMicrobiology