Author

A. A. McBride

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:chromatin & epigenetic regulation· 3 Assay:ChIP-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Warburton· 2 shared T. E. Markowitz· 2 shared J. Kabat· 1 shared J. L. Miranda· 1 shared J. M. Pipas· 1 shared J. P. Katz· 1 shared K. S. Pollard· 1 shared K. Van Doorslaer· 1 shared

Activity by Year

2017-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Warburton

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4 papers

Recent·Most cited

Recurrent Integration of Human Papillomavirus Genomes at Transcriptional Regulatory Hubs

A. Warburton, T. E. Markowitz, J. P. Katz, J. M. Pipas, A. A. McBride

The paper identifies recurrent HPV integration hotspots at transcriptional regulatory hubs in cervical and head and neck cancers, linking them to oncogene expression and carcinogenesis.

npj Genomic Medicine · Nov 30, 2021Peer-reviewedCancer Biology

Histone Variant macroH2A1 Spatially and Functionally Organizes Human Papillomavirus Replication Foci in the Productive Stage of Infection

S. Khurana, T. E. Markowitz, J. Kabat, A. A. McBride

This study shows macroH2A1 spatially organizes HPV replication foci by separating replication and transcription activities in differentiated cells.

bioRxiv · Jul 27, 2021 · PreprintMicrobiology

Sequences in the Human papillomavirus Type 18 (HPV18) Upstream Regulatory Region regulate Viral Genome Replication, Establishment and Persistence

T. L. Coursey, K. Van Doorslaer, A. A. McBride

The paper identifies that the chromatin architecture, rather than specific elements, in the HPV18 upstream regulatory region is crucial for efficient viral genome replication and persistence.

bioRxiv · Feb 22, 2021Microbiology

The Epstein-Barr virus episome maneuvers between nuclear chromatin compartments during reactivation

S. A. Moquin, S. Thomas, S. Whalen, A. Warburton, S. G. Fernanadez, A. A. McBride, K. S. Pollard, J. L. Miranda

This paper shows that the Epstein-Barr virus episome shifts between repressive and active nuclear compartments during latency and reactivation, using interchromosomal interactions to regulate transcription.

bioRxiv · Aug 17, 2017Microbiology