Genetic deletion and pharmacologic inhibition of FcER1 reduces renal injury in mouse models of diabetic nephropathy.
P. Rashmi, A. A. Silva, T. Sigdel, I. Damm, A. L. F. Gouvea, S. Koliwad, V. Walavalkar, S. Hakroush, M. M. Sarwal
This study shows that reducing FcER1 signaling in mouse models of diabetic nephropathy decreases proteinuria and kidney damage.
bioRxiv · Sep 10, 2022 · PreprintImmunology