The neutralization effect of Montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies
S. Durdagi, T. Avsar, M. D. Orhan, M. Serhatli, B. K. Balcioglu, H. U. Ozturk, A. Kayabolen, Y. Cetin, S. Aydinlik, T. Bagci-Onder, S. Tekin, H. Demirci, M. Guzel, A. Akdemir, S. Calis, , Y. Yumak
This paper shows Montelukast inhibits SARS-CoV-2 by targeting both Spike/ACE2 and main protease through in silico and in vitro studies.
bioRxiv · Dec 26, 2020Biophysics