Tracking genome evolution in single cell clones reveals the rates and features of copy number alterations generated by ongoing chromosomal instability in cancer.
S. E. McClelland, M. A. Guscott, D. Gomez-Peregrina, A. Andersen, T. Soliman, C. Vidal-Horrach, B. Bakker, D. C. J. Spierings, R. Wardenaar, F. Foijer, C. Serrano, R. Schwarz
The paper tracks genome evolution in single-cell clones to reveal copy number alteration rates and features in cancer driven by chromosomal instability.
bioRxiv · Sep 27, 2023 · PreprintCancer Biology