Aggregated and hyperstable damage-associated molecular patterns are released during ER stress to modulate immune function
A. Andersohn, I. Garcia, Y. Fan, M. C. Thompson, A. M. Akimzhanov, A. Abdullahi, M. G. Jeschke, D. Boehning
The paper shows chronic ER stress releases protease-resistant DAMPs that activate dendritic cells and drive persistent inflammation.
bioRxiv · May 29, 2019Cell Biology