Phosphoprotein dynamics of interacting tumor and T cells by HySic
S. Ibanez-Molero, J. Pruijs, A. Atmopawiro, F. Wang, M. Altelaar, D. S. Peeper, K. E. Stecker
This paper introduces HySic, a method to quantify protein and phosphorylation dynamics between interacting tumor and T cells, revealing the RHO/RAC/PAK1 pathway's activation and its role in T cell-mediated tumor killing.
bioRxiv · Jun 5, 2023 · PreprintCancer Biology