Author

K. E. Stecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Akhmanova· 3 shared C. M. van den Berg· 2 shared M. Dogterom· 2 shared V. A. Volkov· 2 shared A. Atmopawiro· 1 shared B. Gigant· 1 shared C. van Hoorn· 1 shared D. S. Peeper· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

A. Akhmanova

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth

H. A. J. Saunders, C. M. van den Berg, R. Hoogebeen, D. Schweizer, K. E. Stecker, R. Roepman, S. C. Howes, A. Akhmanova

The paper investigates the interactions of ciliary tip proteins and their role in microtubule dynamics, finding that they form structures that slow and processively elongate microtubules.

bioRxiv · Mar 25, 2024Cell Biology

Phosphoprotein dynamics of interacting tumor and T cells by HySic

S. Ibanez-Molero, J. Pruijs, A. Atmopawiro, F. Wang, M. Altelaar, D. S. Peeper, K. E. Stecker

This paper introduces HySic, a method to quantify protein and phosphorylation dynamics between interacting tumor and T cells, revealing the RHO/RAC/PAK1 pathway's activation and its role in T cell-mediated tumor killing.

bioRxiv · Jun 5, 2023 · PreprintCancer Biology

CSPP1 stabilizes growing microtubule ends and damaged lattices from the luminal side.

C. M. van den Berg, V. A. Volkov, S. Schnorrenberg, Z. Huang, K. E. Stecker, I. Grigoriev, S. Patzke, T. Zimmermann, M. Dogterom, A. Akhmanova

This study identifies CSPP1 as a microtubule stabilizer that binds to growing and damaged microtubules, providing insights into its role in ciliary and centriolar structure maintenance.

bioRxiv · Jun 23, 2022Cell Biology

Microtubule plus-end regulation by centriolar cap proteins

F. E. Ogunmolu, S. Moradi, V. A. Volkov, C. van Hoorn, J. Wu, N. Andrea, S. Hua, K. Jiang, I. A. Vakonakis, M. Potocnjak, F. Herzog, B. Gigant, N. Gudimchuk, K. E. Stecker, M. Dogterom, , A. Akhmanova

The paper investigates how CP110 and CEP97 regulate microtubule plus-end dynamics and centriole biogenesis through direct interactions and synergistic effects.

bioRxiv · Dec 29, 2021 · PreprintCell Biology