Impact of branching on the conformational heterogeneity of the lipopolysaccharide from Klebsiella pneumoniae: Implications for vaccine design
A. Aytenfisu, R. Simon, A. MacKerell
This paper uses molecular dynamics simulations to study how branching in Klebsiella pneumoniae LPS affects conformational states and antigenicity, suggesting a vaccine strategy targeting D-Gal-III with cross-reactivity experiments.
bioRxiv · Dec 18, 2018Biophysics