Addition of adjuvant to DTaP modulates vaccine-induced immunological responses but is insufficient to improve protection in CD-1 mice
K. L. Weaver, G. M. Pyles, S. R. Dublin, A. B. Huckaby, S. J. Miller, M. d. l. P. Gutierrez, E. Sen-Kilic, W. T. Witt, D. T. Boehm, F. H. Damron, M. Barbier
This study evaluates if adding adjuvants to DTaP improves protection in CD-1 mice against Bordetella pertussis, finding that while adjuvants enhance immune markers, they do not improve protection.
bioRxiv · Mar 3, 2023 · PreprintImmunology