An optimized live bacterial delivery platform for the production and delivery of therapeutic nucleic acids and proteins
D. S. O. Mora, M. Cox, F. Magunda, A. B. Williams, L. Linke
This paper develops a live bacterial delivery platform using engineered Escherichia coli to deliver therapeutic nucleic acids and proteins, demonstrating its efficacy in gene silencing and viral mitigation in vivo.
bioRxiv · Oct 17, 2021 · PreprintMicrobiology