Recombinant expression in E. coli of human FGFR2 with its transmembrane and extracellular domains
This study expresses a functional human FGFR2 construct in E. coli containing its transmembrane and extracellular domains, showing it binds heparin and dimerizes but does not form complexes with FGF1 or adopt an inactive dimer conformation.
bioRxiv · May 25, 2017Biochemistry