Adipocyte differentiation of 3T3-L1 cells under TAF, TDF and INSTIs selective challenge: an in vitro model.
A. Perna, M. A. Carleo, S. Mascolo, A. Guida, M. Contieri, C. Sellitto, E. Hay, P. De Blasiis, A. Lucariello, G. Guerra, A. Baldi, A. De Luca, P. Maggi, V. Esposito
This study investigates the effects of INSTIs and NRTIs on adipogenesis in 3T3-L1 cells, finding that TAF and TDF inhibit adipogenesis and counteract INSTI-induced effects.
bioRxiv · Jul 16, 2022Pharmacology & Toxicology