Targeting high-density aromatic peptides to cardiolipin optimizes the mitochondrial membrane potential.
A. Birk, S. Liu, V. Garcia-Marin, M. A. MacNeil
This paper develops a high-density aromatic peptide (HDAP2) that targets cardiolipin to optimize mitochondrial membrane potential, enhancing cell survival and preventing depolarization.
bioRxiv · Sep 28, 2023 · PreprintBiochemistry