Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells
A. D'Souza, A. Burch, K. M. Dave, A. Sreeram, M. S. Reynolds, D. X. Dobbins, Y. S. Kamte, W. Zhao, C. Sabatelle, G. M. Joy, V. Soman, U. R. Chandran, S. Shiva, N. Quillinan, P. S. Herson, D. S Manickam
This paper shows that microvesicles transfer mitochondria to brain endothelial cells and neurons, increasing ATP levels under ischemic conditions, while exosomes do not affect mitochondrial function.
bioRxiv · Apr 10, 2021Bioengineering