Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
G. Bertolin, M.-C. Alves-Guerra, A. Cheron, A. Burel, C. Prigent, R. Le Borgne, M. Tramier
This study identifies AURKA's role in inducing mitophagy via a tripartite complex with PHB2 and MAP1LC3, and shows that Xanthohumol can block this process.
bioRxiv · Apr 6, 2020Cell Biology