A conserved amino acid in the C-terminus of HPV E7 mediates binding to PTPN14 and repression of epithelial differentiation
J. Hatterschide, A. C. Brantly, M. Grace, K. Münger, E. A. White
This paper identifies a conserved arginine residue in HPV E7 that mediates PTPN14 binding and repression of keratinocyte differentiation, contributing to HPV carcinogenesis.
bioRxiv · May 22, 2020Microbiology