Clostridioides difficile PCR ribotype 151 is polyphyletic and includes pathogenic isolates from cryptic clade C-II with mono-toxin pathogenicity loci that can escape routine diagnostics
Q. R. Ducarmon, T. van der Bruggen, C. Harmanus, I. M. J. G. Sanders, L. G. M. Daenen, A. C. Fluit, R. H. A. M. Vossen, S. L. Kloet, E. J. Kuijper, W. K. Smits
The paper identifies that PCR ribotype 151 of Clostridioides difficile is polyphyletic, includes both non-toxigenic and toxigenic isolates, and contains pathogenic variants that evade routine diagnostics.
bioRxiv · Aug 17, 2022 · PreprintMicrobiology