Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest
A. C. Adams, A. M. Macy, P. Kang, K. F. Castro-Ochoa, E. M. K. Wijeratne, Y.-M. Xu, M. X. Liu, A. Charos, M. W. Bosenberg, A. A. L. Gunatilaka, A. R. Sertil, K. T. Hastings
This study shows that physachenolide C induces complete regression of established murine melanoma tumors through apoptosis and cell cycle arrest, with durable responses in some mice.
bioRxiv · May 27, 2021Cancer Biology