Oncogenic context shapes the fitness landscape of tumor suppression
L. M. Blair, J. M. Juan, L. Sebastian, V. B. Tran, W. Nie, G. D. Wall, M. Gerceker, I. K. Lai, E. A. Apilado, G. Grenot, D. Amar, G. Foggetti, M. Do Carmo, Z. Ugur, D. Deng, , I. P. Winters
The paper models tumor suppression fitness landscapes across four oncogenic contexts and finds context-specific tumor suppressor effects.
Nature Communications · Oct 12, 2023Peer-reviewedCancer Biology