Linking CFTR modulators to opportunistic bacterial infections in cystic fibrosis
C. Cigana, R. Giannella, A. Colavolpe, B. Alcalá-Franco, G. Mancini, F. Colombi, C. Bigogno, U. Bastrup, G. Bertoni, A. Bragonzi
This study investigates how CFTR modulators interact with bacterial infections in CF, showing direct antimicrobial effects and enhanced antibiotic activity, while also highlighting the impact of infection on drug exposure.
bioRxiv · Feb 15, 2022Microbiology