Addition of Daptomycin to Levofloxacin Increased the Efficacy of Levofloxacin Monotherapy against a Methicillin-Susceptible Staphylococcus aureus Strain in Experimental Meningitis and Prevented Development of Resistance
P. Cottagnoud, F. Sprenker, M. Cottagnoud, A. Collaud, R. Ashkbus, V. Perreten
This study shows that combining daptomycin with levofloxacin improves antibacterial activity against S. aureus in meningitis and reduces resistance development in vitro.
bioRxiv · Oct 28, 2020Microbiology