Author

A. Cornelius

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 6 Organism:human· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

B. M. Dcosta· 3 shared M. J. Mulligan· 3 shared N. R. Landau· 3 shared T. Tada· 3 shared A. Bosshart· 2 shared A. Neculcea· 2 shared A. Schlegel· 2 shared C. Iss· 2 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

B. M. Dcosta

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Bacterial strain-dependent dissociation of cell recruitment and cell-to-cell spread in early M. tuberculosis infection

B. S. Zha, L. Desvignes, T. Fergus, A. Cornelius, T.-Y. Cheng, D. B. Moody, J. D. Ernst

This study compares early infection dynamics of two M. tuberculosis strains, showing strain-specific differences in bacterial spread and immune activation.

bioRxiv · May 10, 2022Immunology

Neutralization of Mu and C.1.2 SARS-CoV-2 Variants by Vaccine-elicited Antibodies in Individuals With and Without Previous History of Infection

T. Tada, H. Zhou, B. M. Dcosta, M. I. Samanovic, A. Cornelius, R. Herati, M. J. Mulligan, N. R. Landau

This study evaluates neutralization of SARS-CoV-2 Mu and C.1.2 variants by vaccine-elicited and convalescent antibodies, finding that vaccine-induced responses remain protective despite partial resistance.

bioRxiv · Oct 19, 2021Immunology

Comparison of Neutralizing Antibody Titers Elicited by mRNA and Adenoviral Vector Vaccine against SARS-CoV-2 Variants

T. Tada, H. Zhou, M. I. Samanovic, B. M. Dcosta, A. Cornelius, M. J. Mulligan, N. R. Landau

This study compares neutralizing antibody titers from mRNA and adenoviral vector vaccines against SARS-CoV-2 variants, finding lower neutralization against variants for Ad26.COV2.S and suggesting a second dose may improve protection.

bioRxiv · Jul 19, 2021Immunology

Neutralization of viruses with European, South African, and United States SARS-CoV-2 variant spike proteins by convalescent sera and BNT162b2 mRNA vaccine-elicited antibodies

T. Tada, B. M. Dcosta, M. Samanovic-Golden, R. S. Herati, A. Cornelius, M. J. Mulligan, N. R. Landau

This study evaluates the neutralizing activity of convalescent sera and BNT162b2 vaccine antibodies against SARS-CoV-2 variants, showing reduced efficacy against B.1.351 due to E484K mutation but overall maintained protection.

bioRxiv · Feb 5, 2021Microbiology

Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants

S. Rothenberger, D. L. Hurdiss, M. Walser, F. Malvezzi, J. Mayor, S. Ryter, H. Moreno, N. Liechti, A. Bosshart, C. Iss, V. Calabro, A. Cornelius, T. Hospodarsch, A. Neculcea, T. Looser, , Vassell

This paper describes ensovibep, a trispecific DARPin that inhibits SARS-CoV-2 variants by targeting the spike protein, showing potent antiviral activity and protection in animal models.

bioRxiv · Feb 3, 2021 · PreprintImmunology

Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates

M. Walser, S. Rothenberger, D. L. Hurdiss, A. Schlegel, V. Calabro, S. Fontaine, D. Villemagne, M. Paladino, T. Hospodarsch, A. Neculcea, A. Cornelius, P. Schildknecht, M. Matzner, M. Haenggi, M. Franchini, , Stittela

This paper develops potent anti-SARS-CoV-2 DARPin therapeutics with low picomolar neutralization efficacy and reports their protective efficacy in a hamster model.

bioRxiv · Aug 25, 2020 · PreprintImmunology

Dynamics of Mycobacterium tuberculosis Ag85B revealed by sensitive ELISA

J. D. Ernst, A. Cornelius, M. Bolz

This study develops a sensitive ELISA to quantify Ag85B secretion in M. tuberculosis and finds it varies by strain and decreases during infection.

bioRxiv · Mar 15, 2019 · PreprintMicrobiology