Author

A. D. Laflin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. S. Fahad· 2 shared B. J. DeKosky· 2 shared B. Madan· 2 shared S. N. Lopez Acevedo· 2 shared A. Nazzari· 1 shared A. S. Olia· 1 shared B. B. Banach· 1 shared C. Yu Chung· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

A. S. Fahad

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immortalization and Functional Screening of Natively Paired Human T Cell Receptor Repertoires

A. S. Fahad, C. Yu Chung, S. N. Lopez Acevedo, N. Boyle, B. Madan, M. F. Gutierrez-Gonzalez, R. Matus-Nicodemos, A. D. Laflin, R. R. Ladi, J. Zhou, J. Wolfe, S. Llewellyn-Lacey, D. Doueck, H. H. Balfour, D. A. Price, B. J. DeKosky

The paper develops a high-throughput method to functionally evaluate natively paired human T cell receptors against multiple pMHCs, validated through affinity-based mapping and sequencing.

Protein Engineering, Design and Selection · Feb 17, 2022Peer-reviewedImmunology

Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

B. B. Banach, G. Cerutti, A. S. Fahad, C.-H. Shen, M. Oliveira de Souza, P. S. Katsamba, Y. Tsybovsky, P. Wang, M. S. Nair, Y. Huang, I. M. Francino Urdaniz, P. J. Steiner, M. Gutierrez-Gonzalez, L. Liu, S. N. Lopez Acevedo, , B. J. DeKosky

This study identifies a public antibody class, IGHV3-53/3-66, with potent SARS-CoV-2 neutralization capabilities through paired heavy and light chain interactions.

bioRxiv · Dec 31, 2020Immunology