HIV-specific T-cell responses reflect substantive in vivo interactions with infected cells despite long-term therapy
E. Stevenson, A. Ward, R. Truong, A. Thomas, S. H. Huang, T. Dilling, S. Terry, J. Bui, T. Mota, A. Danesh, G. Lee, A. Gramatica, P. Khadka, W. C. Alberto, R. Gandhi, , R. B. Jones
The paper shows HIV-specific T-cell responses persist despite long-term ART, indicating ongoing recognition of infected cells and suggesting the reservoir is not fully immunologically silent.
bioRxiv · Aug 28, 2020Immunology